The Effect of Moringa Oleifera Leaf Extracts Supplementation in Preventing Maternal Anemia and Low-Birth-Weight: A clinical study
by Organic Kosha April 3, 2021
The present study was carried out to investigate the efficacy and safety of Moringa Oleifera Leaf Extracts Supplementation in Preventing Maternal Anemia and Low-Birth-Weight: A clinical study
Treatment Offered
The study design was double-blind, randomized, pretest-posttest controlled. The first-trimester pregnant women that meet the inclusion and exclusion criteria were recruited consecutively. Sixty-four pregnant women enrolled, randomized to intervention and controlled group. The intervention conducted for 90 days from 12-20 weeks of pregnancy age. The intervention group received one capsule of Moringa Oleifera extracts in the morning and one capsule of iron and folic acid in the night. Subjects in the control group received placebo capsules in the morning as well as iron and folic acid capsule in the night. Bodyweight measure, mid-upper arm circumference, and food recall conducted at the end of the fourth, eighth, and twelfth week. Biochemical examination (posttest) conducted in the thirteenth week. The weight and the length of the newborn measure conducted within one hour after the birth.
Results
The anemia status of pregnant women in pre and post-intervention in both intervention and control groups can be seen in Table 1. Below.
Table 1. Anemia status of pregnant women pre and post-intervention.
Table 1. The above shows that hemoglobin levels in the intervention group significantly increased (p<0.05), but the difference in hemoglobin level increase is not significant (p>0.05). The intervention group has a 0.73 gr/dl hemoglobin level increase, while in the control group the increase was only 0.21 gr/dl. An average decrease of ferritin in the intervention group 20.6 µg/ml, while in the control group 38.5 µg/ml. The decrease ferritin level in both groups was significant (p<0.05) but the decrease difference were not significant (p>0.05). Erythrocyte and hematocrit level
Conclusion
In conclusion, Moringa oleifera leaf extracts have a significant effect to increase hemoglobin levels in pregnant women, could prevent ferritin serum dismount to 50%. Low-birth-weight was not found on the pregnant women in the intervention group, while there are 3.20% low-birth-weight in the pregnant women in the control group. Further research is needed to confirm the exact dose of Moringa oleifera leaf extracts.
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