The Effect of Moringa Oleifera Leaf Extracts Supplementation in Preventing Maternal Anemia and Low-Birth-Weight: A clinical study
The present study was carried out to investigate the efficacy and safety of Moringa Oleifera Leaf Extracts Supplementation in Preventing Maternal Anemia and Low-Birth-Weight: A clinical study
The study design was double-blind, randomized, pretest-posttest controlled. The first-trimester pregnant women that meet the inclusion and exclusion criteria were recruited consecutively. Sixty-four pregnant women enrolled, randomized to intervention and controlled group. The intervention conducted for 90 days from 12-20 weeks of pregnancy age. The intervention group received one capsule of Moringa Oleifera extracts in the morning and one capsule of iron and folic acid in the night. Subjects in the control group received placebo capsules in the morning as well as iron and folic acid capsule in the night. Bodyweight measure, mid-upper arm circumference, and food recall conducted at the end of the fourth, eighth, and twelfth week. Biochemical examination (posttest) conducted in the thirteenth week. The weight and the length of the newborn measure conducted within one hour after the birth.
In conclusion, Moringa oleifera leaf extracts have a significant effect to increase hemoglobin levels in pregnant women, could prevent ferritin serum dismount to 50%. Low-birth-weight was not found on the pregnant women in the intervention group, while there are 3.20% low-birth-weight in the pregnant women in the control group. Further research is needed to confirm the exact dose of Moringa oleifera leaf extracts.
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