Clinical Trial of the Spermatogenic Activity of Ashwagandha


Ashwagandha (Withania Somnifera) is a widely used herb in Ayurvedic medicine for vitality, rejuvenation, reduce stress and enhance wellbeing. It nourishes the muscle and bone tissues while supporting a healthy joint movement.

It has also been described in traditional Indian Ayurvedic medicine as an aphrodisiac that can be used to treat male sexual dysfunction and infertility

This pilot study was conducted to evaluate the spermatogenic activity of Ashwagandha root in oligospermic patients.

Details on Participants

Forty-six male patients with oligospermia (sperm count < 20€‰million/mL semen) were enrolled.

Study group:

Two Random groups of 25 and 21 male patients were created for treatment. One group of 21 males were treated with Ashwagandha. The other group of 25 males were administered with to a placebo (a pill with no active medication) .


A dosage of 675€‰mg/d in three doses for 90 days was administer to the 1st group in which Ashwagandha was used from treatment.

The same protocol was administered to the 2nd group to which placebo was used for treatment.



Semen parameters and serum hormone levels were estimated at the end of 90-day treatment.

There was a

  • 167% increase in sperm count
  • 53% increase in semen volume, and
  • 57% increase in sperm motility on day 90 from baseline.

The improvement in these parameters was minimal in the placebo-treated group.

Furthermore, a significantly greater improvement and regulation were observed in serum hormone levels with the Ashwagandha treatment as compared to the placebo.

The present study adds to the evidence on the therapeutic value of Ashwagandha (Withania somnifera), as attributed in Ayurveda for the treatment of oligospermia leading to infertility.

To read the detailed research experiment, please click here.

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